USDA Approves Hardjo-bovis Vaccines

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USDA has approved Titanium 5 L5 and Master Guard 10 vaccines as an aid in preventing disease caused by Leptospira borgpetersenii hardjo-bovis in beef and dairy cattle.

Master Guard 10 HB is a combination modified-live and killed vaccine that provides five-way viral and five-way Leptospira protection in a single dose, while enabling cows to maintain milk production. Master Guard 10’s killed BVD (types 1 and 2) and infectious bovine rhinotracheitis (IBR) fractions offer safety at any stage of lactation; its modified-live parainfluenza3 (PI3) and bovine respiratory syncytial virus (BRSV) fractions maximize immune response. Master Guard may be administered to healthy dairy and beef cattle at least five months of age, including pregnant cows.

Titanium 5 L5 HB is a modified-live vaccine that provides five-way viral and five-way Leptospira protection. Titanium was the first vaccine to protect against both type 1 and type 2 BVD, and offers protection against IBR, PI3 and BRSV. Titanium 5 L5 may be administered to healthy dairy and beef cattle that are not pregnant or nursing.

Both vaccines are available exclusively from AgriLabs. The newly labeled Titanium 5 L5 HB is packaged in five-, 10- and 25-dose boxes, and Master Guard 10 HB is available in 10- and 25-dose boxes. Contact Agrilabs at (800) 542-8916 or


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