Pulmotil® (tilmicosin) is an innovative bovine respiratory disease (BRD) treatment for groups of cattle in the early stages of an outbreak that provides 14 days of sustained in-feed therapy, a practice that reduces stress associated with cattle handling. Ideal for cattle not requiring metaphylaxis treatment on arrival and/or when labor resources are limited, feeding Pulmotil means fewer pulls and less individual animal management.

Since the initial approval of Pulmotil in 2011, Elanco has been working with veterinarians and nutritionists to provide training on the VFD process and conduct further research trials. Pulmotil is now widely available to commercial operations, and we want to ensure you have the information you need to evaluate Pulmotil, develop appropriate protocols, answer client questions and fulfill the requirements for issuing a VFD.

For a brief introduction to Pulmotil, review the Pulmotil Overview Brochure. The brochure discusses the benefits of Pulmotil, research demonstrating its efficacy and the process for implementing a veterinary feed directive (VFD). For more in-depth information, the Pulmotil User Guide has been developed to help you understand the Pulmotil label, and explain how to initiate a VFD and implement a Pulmotil control program. Further directions for planning and preparation, feeding and mixing, and other helpful information are also included. Your Elanco representative or technical consultant can provide you with a copy of the Pulmotil User Guide.

Four studies1 were conducted to collect data for the U.S. Food and Drug Administration registration and approval of Pulmotil in cattle and to demonstrate the efficacy of Pulmotil. At the completion of the studies, the number of calves classified as healthy was greater in Pulmotil-fed calves compared to a control group, 67.3% vs. 49.2% (P = 0.03). A summary of this research can be found in the Pulmotil Tech Report.

The VFD Quick-Start Checklist provides step-by-step instructions for completing a VFD form. The checklist also provides formulas and a reference chart for calculating feed intake and grams per ton, and includes a sample VFD form. VFD form pads of 50 can be ordered through your Elanco representative.

For more information on Pulmotil or the VFD process, contact an Elanco sales representative or visit www.elanco.us.

The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.

Feeds containing tilmicosin must be withdrawn 28 days prior to slaughter.

CAUTION: Federal law limits this drug to use under the professional supervision of a licensed veterinarian. Animal feed bearing or containing this veterinary feed directive drug shall be fed to animals only by or upon a lawful veterinary feed directive issued by a licensed veterinarian in the course of the veterinarian’s professional practice.


For the control of Bovine Respiratory Disease (BRD) in groups of beef and non-lactating dairy cattle, where active BRD has been diagnosed in at least 10% of the animals in the group: Feed continuously for a single, 14-day period at 568 to 757 g/ton of tilmicosin (100% DM basis) in a Type C medicated feed as the sole ration to provide 12.5 mg/kg of body weight/hd/d.

1Pulmotil 90 Freedom of Information Summary (NADA 141-064).

Elanco, Pulmotil® and the diagonal bar are trademarks owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.