Antibiotic use in animal agriculture has been big news lately, with the release of FDA’s Veterinary Feed Directive rule and the White House Forum on Antibiotic Stewardship. This timeline provides milestones in the government’s efforts to promote judicious use of antimicrobials.

April 13, 2012 – FDA issues Guidance for Industry 209: “The Judicious Use of Medically Important Antimicrobial Drugs in Food-Producing Animals,” outlining the agency’s strategy for addressing antimicrobial resistance.

December 12, 2013 – FDA issues Guidance for Industry 213, with recommendations for implementing recommendations in Guidance 209 and removing animal-performance label claims for medically important antimicrobials.

December 12, 2013 – FDA issues its proposed Veterinary Feed Directive (VFD) rule, calling for veterinary supervision of medically important drugs used in feed or water.

June 30 2014 – FDA announces that all 26 affected drug sponsors agreed to voluntarily withdraw label claims in accordance with Guidance 213.

March 27, 2015 – The White House released its National Action Plan for Combating Antibiotic-Resistant Bacteria.

June 2, 2015 – The Obama Administration convened a “White House Forum on Antibiotic Stewardship.” President Obama signed a Presidential Memorandum directing federal agencies to create a preference for meat and poultry produced according to responsible antibiotic-use when making food purchases.

June 3, 2015 – FDA publishes its final VFD rule, amending regulations regarding VFD drugs and mandating veterinary supervision for use of most feed-grade antimicrobials.

October 1, 2015 – The VFD rule published in June takes effect.

December 12, 2016 – Target date for full implementation of Guidance 2013, including removal of animal-performance claims from medically important antimicrobials and transition of use of those products for disease prevention or control to the supervision of veterinarians.